The Hodgkin Huxley Experiments

  1. Achivement:

The All or None Spike and the Voltage Clamp

  1. What are the membrane currents underlying the spike?:钳住电压,分析该电压下膜电流的情况

Membrane Currents Underlying the Spike

  1. Modeling the Membrane Currents::n

The H&H Spike Model

  1. K current::当a越大,β越小,越靠近open。
  2. Na current:
  3. Voltage-dependent Ion channels:
  4. :随着刺激的增强,spike出现提前
  5. 不应期:两个spike之间间隔着10msec,不应期间不能得到另一个spike:The refractory period is caused by close-to-zero values of h.