The Hodgkin Huxley Experiments
- Achivement:


The All or None Spike and the Voltage Clamp

- What are the membrane currents underlying the spike?
注:钳住电压,分析该电压下膜电流的情况
Membrane Currents Underlying the Spike




- Modeling the Membrane Currents:

注:n


The H&H Spike Model
- K current:

注:当a越大,β越小,越靠近open。 - Na current:



- Voltage-dependent Ion channels:



注:随着刺激的增强,spike出现提前- 不应期:两个spike之间间隔着10msec,不应期间不能得到另一个spike
注:The refractory period is caused by close-to-zero values of h.