The Hodgkin Huxley Experiments
- Achivement:
The All or None Spike and the Voltage Clamp
- What are the membrane currents underlying the spike?注:钳住电压,分析该电压下膜电流的情况
Membrane Currents Underlying the Spike
- Modeling the Membrane Currents:注:n
The H&H Spike Model
- K current:注:当a越大,β越小,越靠近open。
- Na current:
- Voltage-dependent Ion channels:
- 注:随着刺激的增强,spike出现提前
- 不应期:两个spike之间间隔着10msec,不应期间不能得到另一个spike注:The refractory period is caused by close-to-zero values of h.